NOVOS Core Extends Lifespan in Aged Mice Beyond Leading Longevity Treatments

We’re thrilled to share findings that underscore the transformative potential of NOVOS Core in supporting wholesome ageing. This latest research highlights NOVOS Core’s capability to increase lifespan by a powerful 18% in aged mice, equal to beginning remedy at 60 human years. The outcomes place NOVOS Core as a frontrunner in shopper anti-aging interventions, outperforming all dietary supplements and lots of the most superior R&D longevity therapies.

Concerning the Examine

The research was carried out at Newcastle College’s Biosciences Institute by a group of esteemed researchers, together with Dr. Thomas von Zglinicki, Professor of Mobile Gerontology with over 43,000 citations, and Dr. Satomi Miwa, Lecturer on the Translational Biology of Getting older with over 10,000 citations. This analysis in contrast NOVOS Core in opposition to each a senolytic drug mixture (a “optimistic management” of interventions beforehand proven to increase mouse lifespan) and a damaging management group with no intervention.

In whole, 38 male mice, aged 20 months at first of the research, had been divided into three teams: a damaging management group, a bunch receiving NOVOS Core, and a senolytic group. Whereas NOVOS Core was administered every day, the senolytic remedy concerned two rounds of injections. Well being markers similar to frailty and cognitive perform had been assessed each two months, including precious insights into NOVOS Core’s impression on general healthspan.

Key Findings from the Examine

This research on NOVOS Core, our patent-pending longevity formulation, uncovered a number of notable outcomes, including vital depth to the scientific understanding of its impression on ageing and healthspan. Right here’s a breakdown of the important thing findings that illustrate why this analysis is groundbreaking:

1. 18% Lifespan Extension in Aged Mice
   NOVOS Core prolonged lifespan by 18% in aged mice, equal to beginning remedy in human 60-year-olds. This spectacular relative enhance surpasses the outcomes of any complement ever studied in aged mice, highlighting NOVOS Core’s effectiveness in selling longevity even when interventions start later in life. The longevity advantages exceed these of different well-known interventions, similar to NR (nicotinamide riboside), glucosamine, and others.
2. A Highly effective, Accessible Different to Complicated Medical Interventions
   The research underscores that NOVOS Core’s pure, multi-ingredient formulation can produce higher lifespan extension outcomes than invasive longevity therapies like TERT gene remedy, senolytic medicine like the mix of dastatanib and quercetin, and hormone therapies like 17-alpha-estradiol. These findings recommend that efficient longevity interventions may be helpful even when began later in life.
3. Similar to R&D Senolytics however with Enhanced Security
   Within the research, NOVOS Core matched the lifespan extension advantages of prescription-grade R&D senolytic injections of navitoclax mixed with BAM15, . Along with these longevity advantages, NOVOS Core delivers real-world health improvements that improve on a regular basis well-being. Not like many of those therapies, which may be invasive or carry potential unwanted side effects, NOVOS Core follows a gentler strategy by leveraging senostatic results—lowering the scale and slowing the formation of senescent cells quite than eliminating them outright. Analysis reveals that not all senescent cells are harmful, and selectively preserving sure senescent cells can profit well being. This balanced strategy supplies a safer, extra sustainable strategy to help longevity.
4. Focusing on All Twelve Mechanisms of Getting older
   NOVOS Core’s unique formulation addresses all twelve scientifically recognized Mechanisms of Aging, a complete strategy that goes past the slim focus of many dietary supplements and therapies. This multi-target technique permits NOVOS Core to ship well being advantages throughout numerous ageing pathways, setting it other than and outperforming single-ingredient therapies like NR, NMN, or much more superior approaches similar to gene remedy.
5. Discount in Frailty and Cognitive Decline
   Along with extending lifespan, NOVOS Core supplied constant, long-term enhancements in well being markers, together with reductions in frailty and preservation of cognitive perform. Whereas trending in direction of statistical significance, the research authors steered that beginning the intervention earlier might yield even stronger outcomes.
6. Enhanced Healthspan: Actual-World Advantages for On a regular basis Effectively-Being
   Past longevity, the identical mechanisms contributing to lifespan extension additionally help high quality of life. These embrace enhancements in pores and skin well being, sleep high quality, power ranges, temper, and cognition—all areas during which NOVOS Core customers have constantly reported optimistic adjustments.

The Implications for Human Well being

Though this research was carried out in mice, its findings maintain promising implications for human well being. NOVOS Core was developed utilizing human research and is particularly formulated to focus on the identical organic pathways that drive ageing in people. The lifespan extension noticed on this research is encouraging, however the speedy well being advantages that NOVOS Core customers report—similar to enhanced power, temper, and cognitive perform—are already making a distinction in every day life.

In essence, NOVOS Core is not only about extending lifespan; it’s about enhancing healthspan—the standard of life within the years we reside. As analysis in longevity science progresses, we’re excited to see NOVOS Core set up itself as a number one, over-the-counter intervention within the anti-aging discipline.

At NOVOS, we’re proud to steer the buyer longevity trade with progressive options backed by rigorous science. By persevering with to put money into third-party analysis and our distinctive strategy to ageing, NOVOS Core stays one of the crucial promising, secure, and accessible longevity options obtainable at the moment.

Learn the preprint of the study here.