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    Home » French startup aims to accelerate drug discovery via ‘digital twins’ of cells
    Longevity

    French startup aims to accelerate drug discovery via ‘digital twins’ of cells

    Team_ KporiaBy Team_ KporiaDecember 17, 2024No Comments3 Mins Read
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    DeepLife secures $10m to advance AI platform designed to establish molecular triggers able to driving diseased cells right into a wholesome state.

    Paris-based biotech DeepLife has efficiently closed a $10 million Sequence A funding spherical. The corporate leverages AI to create so-called “digital twins” of human cells to assist drug discovery and therapeutic growth.

    Based in 2019 by Jonathan Baptista, an skilled in simulation instruments for aeronautics, and Jean-Baptiste Morlot, a researcher in AI functions for genetics and epigenetics, DeepLife harnesses multi-omics knowledge, techniques biology and generative AI to handle inefficiencies in drug growth processes. On the coronary heart of the corporate’s method is its Cell Blueprint platform, a classy instrument designed to map mobile networks and uncover therapeutic methods tailor-made to particular cell varieties.

    Combining “one of many world’s largest” multi-omics databases with state-of-the-art AI fashions and curated scientific literature, Cell Blueprint offers insights into the molecular mechanisms of cells, supporting the identification of triggers able to driving diseased cells again to a wholesome state. The platform permits researchers to simulate drug results on the mobile stage, opening potentialities for therapies concentrating on situations beforehand thought of undruggable.

    Claiming its know-how has already attracted the eye of “main business gamers,” Baptista, DeepLife’s CEO, mentioned: “By pushing the boundaries of AI and biology, we purpose to uncover therapies for illnesses as soon as thought untreatable, making a future the place no illness is past attain.”

    In keeping with DeepLife, the Cell Blueprint platform helps a number of functions throughout the drug growth ecosystem. In goal discovery and validation, it permits exact evaluation of cell-type-specific networks, simplifying the identification of distinctive pathways vital to particular cell varieties. For biomarker discovery, the platform’s means to dissect mobile networks ensures the identification of sturdy, constant biomarkers, enhancing diagnostic precision. In drug repurposing, it addresses a key problem by predicting drug results on particular cell networks, decreasing off-target dangers and enhancing success charges. Lastly, the platform sheds gentle on the mechanisms of complicated illnesses by differentiating disease-associated networks throughout cell varieties, thereby guiding the event of focused therapeutic interventions.

    The Sequence A funding, led by YZR Capital and Relyens Innovation Santé with assist from Beiersdorf Enterprise Capital, Prunay Group and current backers, will enable DeepLife to additional develop its digital twin platform and validate its potential utility in autoimmune and neurodegenerative illnesses.

    “DeepLife’s distinctive answer combining multi-omics databases and cutting-edge AI fashions to create digital twins of cells holds immense potential not only for revolutionizing drug discovery but additionally for functions starting from biomanufacturing to precision drugs,” mentioned Turenne Capital’s Claire Poulard.

    {Photograph}: claudioventrella/Envato

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