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By TREVOR VAN MIERLO
In 2021, digital psychological well being and substance use startups attracted a record-breaking $5.1 billion in funding. Regardless of the surge, the promise of scalable, transformative digital well being platforms stays unfulfilled.
Following the surge, funding plummeted. Not like different industries which were revolutionized by digital-first options, digital well being struggles with fashions that fail to handle price, complexity, and entry.
What we’re left with getting into into 2025 are a smorgasbord of options clamoring to connect themselves to conventional enterprise incumbents (Well being Insurance coverage Suppliers, Digital Well being Information, Hospital Methods). These incumbents have achieved scale – however not the kind of scale that digital well being must flourish.

Incumbents Construct Deep, Startups Go Large
Incumbent scale is infrastructure-heavy, gradual, and linear, and focuses on deep integration inside their established markets.
In distinction, startups intention for technology-driven, exponential, and world scale, leveraging digital platforms to serve thousands and thousands of customers shortly. Whereas startups have the velocity benefit, reaching scale just like incumbents requires win-win partnerships and basic shifts away from established enterprise fashions.

The funding market does see the great alternative: an enormous, rising world customer-base proactively demanding assist as social stigma decreases. And as time passes, this customer-base grows exponentially with know-how pervasiveness.
What buyers see is unmet demand for psychological well being and substance use remedy, and a historic alternative for digital well being to step up and ship options which might be scalable, accessible, and reasonably priced.
Nevertheless, the supply mechanism to those populations, although digital, is obfuscated by the blurred lens of incumbent buying energy. We are able to’t get previous incumbents’ measurement, their attain, and their connection to sufferers. On this widespread view, incumbents are the client. This view is promoted by each business and academia.
A latest HLTH Inc. abstract, titled Boston Think Tank: Event Takeaways – Scaling Digital Health: De-Risking Adoption summarizes this: “To successfully scale digital well being options, a fastidiously crafted technique is required – one which meets the intricate calls for of healthcare techniques whereas navigating potential adoption hurdles“.
Final April a JMIR Publications printed Digital Health at Enterprise Scale: Evaluation Framework for Selecting Patient-Facing Software in a Digital-First Health System. It begins: “The digital transformation of our well being care system would require not solely digitization of current instruments but in addition a redesign of our care supply system and collaboration with digital companions.“
Each will take a long time to attain, and the market gained’t wait. The client is just not the incumbent. The client is just not even sufferers – it’s folks.
For now, demand surges, however digital well being is stuck in the middle.
Demand Surge: Psychological Well being & Substance Use TAM, SAM, and SOM
To grasp the size of the chance in digital psychological well being and addictions, we flip to TAM (Complete Addressable Market), SAM (Service Out there Market), and SOM (Serviceable Obtainable Market) – frameworks broadly utilized by buyers to judge market potential. The framework is summarized properly by Ali Gamaleldin here.
The TAM, SAM, and SOM in psychological well being and addictions represents a unprecedented, if not immense, enterprise alternative far surpassing many different industries in scope. The dimensions of the market is a results of excessive prevalence (1 in 8 residents), persistent demand, and world scalability after the correct resolution is applied.
In North America and Europe alone, the annual TAM for psychological well being and substance use help is at the moment estimated at $1.2 trillion.

In Australasia the TAM, SAM, and SOM are estimated at $60, $15, and $3 billion, respectively. A scarcity of complete epidemiological knowledge prohibits the TAM, SAM, and SOM from being calculated for Asia, however development alternatives are huge. That is just like Central and South America, that are additional compounded by various economies and cultures, government-led healthcare techniques, and cultural perceptions of psychological well being.
However regardless of setbacks in Asia, Central, and South America, the varied, multicultural societies in North America and Europe can actively check and validate these rising markets. These areas are ripe for follow-on growth and digital scale.
However has this been achieved earlier than? What different industries have addressed alternatives with excessive TAM, SAM, and SOM? Is there a roadmap?
The Present Market and Roadmaps
Rock Health Capital appeared optimistic about 2024. Nevertheless, in actuality digital psychological well being corporations solely raised $682 million within the first half. MedTech Strategist replicate this cautious optimism, and Galen Growth | Insights You Can Trust states that digital well being is poised to outperform 2023, however with the funding specializing in AI are these numbers indicative of digital well being breakthroughs?
There are a number of components behind the speedy lower in funding from 2021, together with a correction attributable to pandemic-driven surge, overvaluations, and investor fatigue, however markets are opportunistic.
However let’s face it – the first purpose is that regardless of the continuing hype surrounding digital well being, a transparent winner – or winners – haven’t emerged. Worse – not like different industries which have remodeled to digital, we nonetheless haven’t seen a worthwhile enterprise mannequin.
Seeking to Different Industries
In different industries, important TAM, SAM, and SOM alternatives have been leveraged to disrupt business incumbents.

Within the above examples, every firm disrupted incumbents by addressing issues like price, complexity, or entry. These of us within the digital well being business have to truthfully ask ourselves if any of the options we’ve created have:
- decreased prices (one may argue healthcare is costlier than ever)
- made the assistance searching for course of and entry much less complicated (attempt to acquire instant entry to a digital well being product)
- opened doorways to non-traditional clients (e.g. non-insured, minimally-insured, college students, and so on.)
Substitutions & Dietary supplements
Digital well being in the present day is dominated by substitutes, like telehealth and digital therapeutics (mimicking conventional care), and dietary supplements (engagement apps and wearables). These instruments improve failing fashions and don’t deal with the TAM.

Neither strategy addresses the core challenges of price, complexity, and entry. True disruption continues to be lacking.
Digital Well being: A Downside in Search of an Reply
Huge parts of digital well being’s TAM stay untapped, and the issue is obvious: whereas the demand for psychological well being and substance use interventions is gigantic, conventional and hybrid fashions – specializing in dissemination by incumbents – fall brief with excessive prices, and restricted scalability.
What’s clear is that the quickly increasing market, which is burgeoning globally, is ripe for disruption.
Catching the breath of digital well being CEOs, product managers, and buyers is that Within the realm of digital well being, a “winner-take-all” situation is fully attainable. Which means a single evidence-based firm or platform may doubtlessly dominate the market by capturing a big majority of customers and market share, producing world community results, leveraging knowledge – and maybe most significantly – making the most of investor fatigue in ventures which might be stagnant.
Digital well being is at a crossroads. To really revolutionize care, we should transfer past incremental enhancements and embrace options that disrupt the established order – options that scale globally, scale back prices, and open doorways for the thousands and thousands ready to leap at accessible care.
Dr. Trevor van Mierlo has constructed psychological well being and affected person assist merchandise for greater than twenty years and is the CEO of Evolution Health
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